Have questions about PLEGRIDY? We have answers.

Select a topic below to read up on treating relapsing MS with PLEGRIDY.

Ways to help manage injection site reactions with PLEGRIDY

How can I manage injection site reactions with PLEGRIDY?

Before the injection:

Rotate (change) the injection site you choose with each injection.

Do not inject into an area of the body where the skin is irritated, reddened, bruised, infected, or scarred.

Allow 30 minutes for the pen or syringe to warm to room temperature before injecting.

Apply warm compresses to the injection site, which may help relax the tissue under your skin.

After the injection:

Gently massage the injection site for 15-30 seconds.

Cool the injection site by placing something cold, such as a gel pack, on the site.

Ask your healthcare provider if applying a topical treatment may help relieve redness or rash.

Check the site 2 hours after injection for redness, pain, itching, swelling, tenderness, or a break in the skin that becomes blue and black or drains fluid. If you have a skin reaction and it does not clear up in a few days, call your healthcare provider right away.

Managing flu-like symptoms with PLEGRIDY

How can I manage flu-like symptoms with PLEGRIDY?

The following tips may help to manage flu-like symptoms:

Ask your healthcare provider about using over-the-counter pain and fever reducers on treatment days.

Stay well hydrated by drinking plenty of water.

Experiment with different times of day for your injection. Symptoms may peak at different times depending on the individual.

Keep a journal to note how long after your injection any side effects occur, how much water you drink, and any pain relievers you take.

Remember, it’s important to talk to a healthcare provider about any side effects you experience.

These are not all of the possible side effects of PLEGRIDY. Call your healthcare provider for medical advice about side effects.


How should I store PLEGRIDY?

Store PLEGRIDY in the refrigerator between 36 to 46 °F (2 to 8 °C).

If you cannot refrigerate your PLEGRIDY Pen and PLEGRIDY prefilled syringes, you can store your PLEGRIDY Pen and PLEGRIDY prefilled syringes at room temperature up to 77 °F (25 °C) for up to 30 days.

Keep PLEGRIDY in the original carton to protect it from light.

Do not freeze PLEGRIDY. Throw out PLEGRIDY that has been frozen.

Do not use PLEGRIDY past the expiration date.

Keep PLEGRIDY Pens, prefilled syringes, and all medicines out of the reach of children.

Throw PLEGRIDY away in an FDA-cleared sharps disposal container if it has not been stored as stated above.

Have a trip coming up? Consider these storage requirements when you travel and talk to your doctor about traveling while on PLEGRIDY.

PLEGRIDY cost coverage

Will my insurance cover the cost of PLEGRIDY?

Approximately 80% of commercially insured patients have a copay of $30 or less per month for PLEGRIDY covered under a pharmacy benefit.*

Plus, PLEGRIDY is preferred on 3 of the nation’s largest health plans/pharmacy benefits managers.
(Formulary status alone does not imply a comparison of the safety, efficacy, or dosage regimens of products for relapsing MS.)

*Based on formulary data provided by Managed Markets Insight & Technology, LLC, which are current as of February 2020.
Based on Breakaway Partners, Drug Coverage Analytics, March 12, 2020. Biogen does not endorse any particular plan. Because formularies change and many health plans offer more than 1 formulary, it is important to check directly with the health plan to confirm coverage for individual patients.

More to explore with PLEGRIDY

Biogen Support Services

If you’re living with relapsing multiple sclerosis (MS), know that you’re not alone. Biogen Support Services is here to help.
Get support today

Want to know more?

Download a list of questions to help start a conversation with your healthcare provider about your relapsing MS treatment.
Download questions

Financial & Insurance Assistance

Get information on insurance coverage and financial assistance options, including the Biogen Copay Program if you are eligible.††
Take a look

MY Planner

Track your treatment with PLEGRIDY and record your injections
Download MY Planner

Support resources

Find additional support for you and your care partners.
Check it out

††There is an annual cap on the amount of assistance that patients can receive over a one-year period. Federal and state laws and other factors may prevent or otherwise restrict eligibility. People covered by Medicare, Medicaid, the VA/DoD, or any other federal plans are not eligible to enroll. You are eligible to enroll in the Biogen Copay Program for as long as it is offered and you are treated with a Biogen relapsing MS medication.

Watch a PLEGRIDY patient video

Hear personal stories from real patients taking PLEGRIDY.